Comparison of saliva and oro-nasopharyngeal swab sample in the molecular diagnosis of COVID-19.
Identifieur interne : 000721 ( Main/Exploration ); précédent : 000720; suivant : 000722Comparison of saliva and oro-nasopharyngeal swab sample in the molecular diagnosis of COVID-19.
Auteurs : Ertu Rul Güçlü [Turquie] ; Mehmet Koroglu [Turquie] ; Yusuf Yürümez [Turquie] ; Hande Toptan [Turquie] ; Elif Kose [Turquie] ; Fatih Güneysu [Turquie] ; O Uz Karabay [Turquie]Source :
- Revista da Associacao Medica Brasileira (1992) [ 1806-9282 ] ; 2020.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- diagnosis : Coronavirus Infections, Pneumonia, Viral.
- Adult, Aged, Betacoronavirus, Clinical Laboratory Techniques, Humans, Male, Middle Aged, Nasopharynx, Pandemics, Saliva.
Abstract
BACKGROUND
Healthcare personnel are at risk of becoming infected while taking upper and/or lower respiratory tract specimens. Therefore, there is a need for sampling methods that do not risk infecting them. In this study, we aimed to compare the saliva and Oro-Nasopharyngeal Swab (ONS) sampling methods.
METHODS
Patients were divided into three groups. Group 1 included patients whose diagnosis of COVID-19 was confirmed by polymerase chain reaction (PCR). Group 2 included patients with COVID-19 compatible findings in lung computed tomography (CT), but with a negative PCR. Group 3 included patients who presented to the emergency department with COVID-19 compatible complaints but had normal CT. Saliva and ONS samples were taken on the third day of hospitalization in groups 1 and 2, whereas in group 3, they were taken at the time of admission to the hospital.
RESULTS
A total of 64 patients were included in the study. The average age was 51.04 ± 17.9 years, and 37 (57.8%) were male. SARS-CoV-2 was detected in 27 (42.2%) patients' saliva samples. While the sensitivity and positive predictive value of saliva samples were 85.2%, specificity and negative predictive value were 89.2%. The value of kappa was in substantial agreement (0.744), and it was found statistically significant (<0.001).
CONCLUSIONS
Saliva samples can be used instead of ONS samples in detecting SARS-CoV-2. Investigating SARS-CoV-2 with saliva is cheaper, easier for the patient and overall, and, most importantly, it poses much less risk of SARS-CoV-2 contamination to healthcare personnel.
DOI: 10.1590/1806-9282.66.8.1116
PubMed: 32935807
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Comparison of saliva and oro-nasopharyngeal swab sample in the molecular diagnosis of COVID-19.</title><author><name sortKey="Guclu, Ertu Rul" sort="Guclu, Ertu Rul" uniqKey="Guclu E" first="Ertu Rul" last="Güçlü">Ertu Rul Güçlü</name><affiliation wicri:level="1"><nlm:affiliation>. Sakarya University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sakarya, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>. Sakarya University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sakarya</wicri:regionArea><wicri:noRegion>Sakarya</wicri:noRegion></affiliation></author><author><name sortKey="Koroglu, Mehmet" sort="Koroglu, Mehmet" uniqKey="Koroglu M" first="Mehmet" last="Koroglu">Mehmet Koroglu</name><affiliation wicri:level="1"><nlm:affiliation>. Sakarya University Faculty of Medicine, Department of Clinic Microbiology, Sakarya, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>. Sakarya University Faculty of Medicine, Department of Clinic Microbiology, Sakarya</wicri:regionArea><wicri:noRegion>Sakarya</wicri:noRegion></affiliation></author><author><name sortKey="Yurumez, Yusuf" sort="Yurumez, Yusuf" uniqKey="Yurumez Y" first="Yusuf" last="Yürümez">Yusuf Yürümez</name><affiliation wicri:level="1"><nlm:affiliation>. Sakarya University, Faculty of Medicine, Department of Emergency Medicine, Sakarya, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>. Sakarya University, Faculty of Medicine, Department of Emergency Medicine, Sakarya</wicri:regionArea><wicri:noRegion>Sakarya</wicri:noRegion></affiliation></author><author><name sortKey="Toptan, Hande" sort="Toptan, Hande" uniqKey="Toptan H" first="Hande" last="Toptan">Hande Toptan</name><affiliation wicri:level="1"><nlm:affiliation>. Sakarya University Faculty of Medicine, Department of Clinic Microbiology, Sakarya, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>. Sakarya University Faculty of Medicine, Department of Clinic Microbiology, Sakarya</wicri:regionArea><wicri:noRegion>Sakarya</wicri:noRegion></affiliation></author><author><name sortKey="Kose, Elif" sort="Kose, Elif" uniqKey="Kose E" first="Elif" last="Kose">Elif Kose</name><affiliation wicri:level="1"><nlm:affiliation>. Sakarya University, Faculty of Medicine, Department of Public Health, Sakarya, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>. Sakarya University, Faculty of Medicine, Department of Public Health, Sakarya</wicri:regionArea><wicri:noRegion>Sakarya</wicri:noRegion></affiliation></author><author><name sortKey="Guneysu, Fatih" sort="Guneysu, Fatih" uniqKey="Guneysu F" first="Fatih" last="Güneysu">Fatih Güneysu</name><affiliation wicri:level="1"><nlm:affiliation>. Sakarya University, Training and Research Hospital, Clinic of Emergency Medicine, Sakarya, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>. Sakarya University, Training and Research Hospital, Clinic of Emergency Medicine, Sakarya</wicri:regionArea><wicri:noRegion>Sakarya</wicri:noRegion></affiliation></author><author><name sortKey="Karabay, O Uz" sort="Karabay, O Uz" uniqKey="Karabay O" first="O Uz" last="Karabay">O Uz Karabay</name><affiliation wicri:level="1"><nlm:affiliation>. Sakarya University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sakarya, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>. Sakarya University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sakarya</wicri:regionArea><wicri:noRegion>Sakarya</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32935807</idno><idno type="pmid">32935807</idno><idno type="doi">10.1590/1806-9282.66.8.1116</idno><idno type="wicri:Area/Main/Corpus">000197</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000197</idno><idno type="wicri:Area/Main/Curation">000197</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000197</idno><idno type="wicri:Area/Main/Exploration">000197</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Comparison of saliva and oro-nasopharyngeal swab sample in the molecular diagnosis of COVID-19.</title><author><name sortKey="Guclu, Ertu Rul" sort="Guclu, Ertu Rul" uniqKey="Guclu E" first="Ertu Rul" last="Güçlü">Ertu Rul Güçlü</name><affiliation wicri:level="1"><nlm:affiliation>. Sakarya University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sakarya, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>. Sakarya University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sakarya</wicri:regionArea><wicri:noRegion>Sakarya</wicri:noRegion></affiliation></author><author><name sortKey="Koroglu, Mehmet" sort="Koroglu, Mehmet" uniqKey="Koroglu M" first="Mehmet" last="Koroglu">Mehmet Koroglu</name><affiliation wicri:level="1"><nlm:affiliation>. Sakarya University Faculty of Medicine, Department of Clinic Microbiology, Sakarya, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>. Sakarya University Faculty of Medicine, Department of Clinic Microbiology, Sakarya</wicri:regionArea><wicri:noRegion>Sakarya</wicri:noRegion></affiliation></author><author><name sortKey="Yurumez, Yusuf" sort="Yurumez, Yusuf" uniqKey="Yurumez Y" first="Yusuf" last="Yürümez">Yusuf Yürümez</name><affiliation wicri:level="1"><nlm:affiliation>. Sakarya University, Faculty of Medicine, Department of Emergency Medicine, Sakarya, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>. Sakarya University, Faculty of Medicine, Department of Emergency Medicine, Sakarya</wicri:regionArea><wicri:noRegion>Sakarya</wicri:noRegion></affiliation></author><author><name sortKey="Toptan, Hande" sort="Toptan, Hande" uniqKey="Toptan H" first="Hande" last="Toptan">Hande Toptan</name><affiliation wicri:level="1"><nlm:affiliation>. Sakarya University Faculty of Medicine, Department of Clinic Microbiology, Sakarya, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>. Sakarya University Faculty of Medicine, Department of Clinic Microbiology, Sakarya</wicri:regionArea><wicri:noRegion>Sakarya</wicri:noRegion></affiliation></author><author><name sortKey="Kose, Elif" sort="Kose, Elif" uniqKey="Kose E" first="Elif" last="Kose">Elif Kose</name><affiliation wicri:level="1"><nlm:affiliation>. Sakarya University, Faculty of Medicine, Department of Public Health, Sakarya, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>. Sakarya University, Faculty of Medicine, Department of Public Health, Sakarya</wicri:regionArea><wicri:noRegion>Sakarya</wicri:noRegion></affiliation></author><author><name sortKey="Guneysu, Fatih" sort="Guneysu, Fatih" uniqKey="Guneysu F" first="Fatih" last="Güneysu">Fatih Güneysu</name><affiliation wicri:level="1"><nlm:affiliation>. Sakarya University, Training and Research Hospital, Clinic of Emergency Medicine, Sakarya, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>. Sakarya University, Training and Research Hospital, Clinic of Emergency Medicine, Sakarya</wicri:regionArea><wicri:noRegion>Sakarya</wicri:noRegion></affiliation></author><author><name sortKey="Karabay, O Uz" sort="Karabay, O Uz" uniqKey="Karabay O" first="O Uz" last="Karabay">O Uz Karabay</name><affiliation wicri:level="1"><nlm:affiliation>. Sakarya University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sakarya, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>. Sakarya University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sakarya</wicri:regionArea><wicri:noRegion>Sakarya</wicri:noRegion></affiliation></author></analytic><series><title level="j">Revista da Associacao Medica Brasileira (1992)</title><idno type="eISSN">1806-9282</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Aged (MeSH)</term><term>Betacoronavirus (MeSH)</term><term>Clinical Laboratory Techniques (MeSH)</term><term>Coronavirus Infections (diagnosis)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Nasopharynx (MeSH)</term><term>Pandemics (MeSH)</term><term>Pneumonia, Viral (diagnosis)</term><term>Saliva (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Betacoronavirus (MeSH)</term><term>Humains (MeSH)</term><term>Infections à coronavirus (diagnostic)</term><term>Mâle (MeSH)</term><term>Pandémies (MeSH)</term><term>Partie nasale du pharynx (MeSH)</term><term>Pneumopathie virale (diagnostic)</term><term>Salive (MeSH)</term><term>Sujet âgé (MeSH)</term><term>Techniques de laboratoire clinique (MeSH)</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Betacoronavirus</term><term>Clinical Laboratory Techniques</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Nasopharynx</term><term>Pandemics</term><term>Saliva</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Betacoronavirus</term><term>Humains</term><term>Mâle</term><term>Pandémies</term><term>Partie nasale du pharynx</term><term>Salive</term><term>Sujet âgé</term><term>Techniques de laboratoire clinique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>Healthcare personnel are at risk of becoming infected while taking upper and/or lower respiratory tract specimens. Therefore, there is a need for sampling methods that do not risk infecting them. In this study, we aimed to compare the saliva and Oro-Nasopharyngeal Swab (ONS) sampling methods.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>Patients were divided into three groups. Group 1 included patients whose diagnosis of COVID-19 was confirmed by polymerase chain reaction (PCR). Group 2 included patients with COVID-19 compatible findings in lung computed tomography (CT), but with a negative PCR. Group 3 included patients who presented to the emergency department with COVID-19 compatible complaints but had normal CT. Saliva and ONS samples were taken on the third day of hospitalization in groups 1 and 2, whereas in group 3, they were taken at the time of admission to the hospital.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>A total of 64 patients were included in the study. The average age was 51.04 ± 17.9 years, and 37 (57.8%) were male. SARS-CoV-2 was detected in 27 (42.2%) patients' saliva samples. While the sensitivity and positive predictive value of saliva samples were 85.2%, specificity and negative predictive value were 89.2%. The value of kappa was in substantial agreement (0.744), and it was found statistically significant (<0.001).</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>Saliva samples can be used instead of ONS samples in detecting SARS-CoV-2. Investigating SARS-CoV-2 with saliva is cheaper, easier for the patient and overall, and, most importantly, it poses much less risk of SARS-CoV-2 contamination to healthcare personnel.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">32935807</PMID><DateCompleted><Year>2020</Year><Month>09</Month><Day>18</Day></DateCompleted><DateRevised><Year>2020</Year><Month>09</Month><Day>18</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1806-9282</ISSN><JournalIssue CitedMedium="Internet"><Volume>66</Volume><Issue>8</Issue><PubDate><Year>2020</Year><Month>Aug</Month></PubDate></JournalIssue><Title>Revista da Associacao Medica Brasileira (1992)</Title><ISOAbbreviation>Rev Assoc Med Bras (1992)</ISOAbbreviation></Journal><ArticleTitle>Comparison of saliva and oro-nasopharyngeal swab sample in the molecular diagnosis of COVID-19.</ArticleTitle><Pagination><MedlinePgn>1116-1121</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0104-42302020000801116</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1590/1806-9282.66.8.1116</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Healthcare personnel are at risk of becoming infected while taking upper and/or lower respiratory tract specimens. Therefore, there is a need for sampling methods that do not risk infecting them. In this study, we aimed to compare the saliva and Oro-Nasopharyngeal Swab (ONS) sampling methods.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Patients were divided into three groups. Group 1 included patients whose diagnosis of COVID-19 was confirmed by polymerase chain reaction (PCR). Group 2 included patients with COVID-19 compatible findings in lung computed tomography (CT), but with a negative PCR. Group 3 included patients who presented to the emergency department with COVID-19 compatible complaints but had normal CT. Saliva and ONS samples were taken on the third day of hospitalization in groups 1 and 2, whereas in group 3, they were taken at the time of admission to the hospital.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 64 patients were included in the study. The average age was 51.04 ± 17.9 years, and 37 (57.8%) were male. SARS-CoV-2 was detected in 27 (42.2%) patients' saliva samples. While the sensitivity and positive predictive value of saliva samples were 85.2%, specificity and negative predictive value were 89.2%. The value of kappa was in substantial agreement (0.744), and it was found statistically significant (<0.001).</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Saliva samples can be used instead of ONS samples in detecting SARS-CoV-2. Investigating SARS-CoV-2 with saliva is cheaper, easier for the patient and overall, and, most importantly, it poses much less risk of SARS-CoV-2 contamination to healthcare personnel.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Güçlü</LastName><ForeName>Ertuğrul</ForeName><Initials>E</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-2860-2831</Identifier><AffiliationInfo><Affiliation>. Sakarya University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sakarya, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Koroglu</LastName><ForeName>Mehmet</ForeName><Initials>M</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-8101-1104</Identifier><AffiliationInfo><Affiliation>. Sakarya University Faculty of Medicine, Department of Clinic Microbiology, Sakarya, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yürümez</LastName><ForeName>Yusuf</ForeName><Initials>Y</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-3917-9434</Identifier><AffiliationInfo><Affiliation>. Sakarya University, Faculty of Medicine, Department of Emergency Medicine, Sakarya, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Toptan</LastName><ForeName>Hande</ForeName><Initials>H</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-6893-8490</Identifier><AffiliationInfo><Affiliation>. Sakarya University Faculty of Medicine, Department of Clinic Microbiology, Sakarya, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kose</LastName><ForeName>Elif</ForeName><Initials>E</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-2232-4538</Identifier><AffiliationInfo><Affiliation>. Sakarya University, Faculty of Medicine, Department of Public Health, Sakarya, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Güneysu</LastName><ForeName>Fatih</ForeName><Initials>F</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-8433-3763</Identifier><AffiliationInfo><Affiliation>. Sakarya University, Training and Research Hospital, Clinic of Emergency Medicine, Sakarya, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Karabay</LastName><ForeName>Oğuz</ForeName><Initials>O</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-1514-1685</Identifier><AffiliationInfo><Affiliation>. Sakarya University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Sakarya, Turkey.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Brazil</Country><MedlineTA>Rev Assoc Med Bras (1992)</MedlineTA><NlmUniqueID>9308586</NlmUniqueID><ISSNLinking>0104-4230</ISSNLinking></MedlineJournalInfo><SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName><SupplMeshName Type="Protocol" UI="C000657964">COVID-19 diagnostic testing</SupplMeshName><SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName></SupplMeshList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="Y">Betacoronavirus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019411" MajorTopicYN="N">Clinical Laboratory Techniques</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="Y">Coronavirus Infections</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009305" MajorTopicYN="N">Nasopharynx</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="Y">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="Y">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012463" MajorTopicYN="N">Saliva</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>05</Month><Day>06</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>05</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>9</Month><Day>16</Day><Hour>8</Hour><Minute>40</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>9</Month><Day>17</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>9</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32935807</ArticleId><ArticleId IdType="pii">S0104-42302020000801116</ArticleId><ArticleId IdType="doi">10.1590/1806-9282.66.8.1116</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Turquie</li></country></list><tree><country name="Turquie"><noRegion><name sortKey="Guclu, Ertu Rul" sort="Guclu, Ertu Rul" uniqKey="Guclu E" first="Ertu Rul" last="Güçlü">Ertu Rul Güçlü</name></noRegion><name sortKey="Guneysu, Fatih" sort="Guneysu, Fatih" uniqKey="Guneysu F" first="Fatih" last="Güneysu">Fatih Güneysu</name><name sortKey="Karabay, O Uz" sort="Karabay, O Uz" uniqKey="Karabay O" first="O Uz" last="Karabay">O Uz Karabay</name><name sortKey="Koroglu, Mehmet" sort="Koroglu, Mehmet" uniqKey="Koroglu M" first="Mehmet" last="Koroglu">Mehmet Koroglu</name><name sortKey="Kose, Elif" sort="Kose, Elif" uniqKey="Kose E" first="Elif" last="Kose">Elif Kose</name><name sortKey="Toptan, Hande" sort="Toptan, Hande" uniqKey="Toptan H" first="Hande" last="Toptan">Hande Toptan</name><name sortKey="Yurumez, Yusuf" sort="Yurumez, Yusuf" uniqKey="Yurumez Y" first="Yusuf" last="Yürümez">Yusuf Yürümez</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/CovidSeniorV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000721 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000721 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= CovidSeniorV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:32935807
|texte= Comparison of saliva and oro-nasopharyngeal swab sample in the molecular diagnosis of COVID-19.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:32935807" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a CovidSeniorV1
| This area was generated with Dilib version V0.6.37. |  |